Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa...
PHASE1
Background:
Malaria remains a major global health problem. Malaria is spre...
A Study to Find Out if a Combination of 3 Medicines for the Treatment of Malaria Works as Well and is as Safe and Tolerable as Combinations of 2 Medicines
PHASE3
The goal of this open-label randomised, controlled, non-inferiority trial i...
Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzania
PHASE3
Background:
In high-transmission settings, up to 70% of school-aged childr...
Safety and Effectiveness of Artemisinin-based Combination Therapies (ACTs) With Repeated Treatments for Uncomplicated Falciparum Malaria Over a Three-year Period
PHASE4
A community-based, open-label, cluster-randomised longitudinal study in whi...
Status
Unknown
Location
Malawi-Liverpool-Wellcome Trust Research Programme, College of Medicine
Efficacy of Artemether-Lumefantrine in the Treatment of Uncomplicated Plasmodium Falciparum Malaria in Children Under 12 Years at Four Sentinel Sites in Mozambique
NA
This is a classical in vivo clinical trial, following World Health organiza...